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Search Results for " peptidylarginine deiminase "

9

Compounds

Cat No. Product Name Synonyms Targets
T8861 GSK199 PAD
GSK199 is a selective PAD4 inhibitor(IC50 of 200 nM in the absence of calcium).
T24105 GSK121 GSK-121,GSK 121 PAD
GSK121 is an inhibitor of selective PAD4.
T22277 BMS-P5 PAD
BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.
T22277L BMS-P5 free base PAD
BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-...
T10831L Cl-amidine hydrochloride Apoptosis , PAD
Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50: 5.9 μM for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro ca...
T2205 Acefylline Theophylline-7-acetic acid,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid TNF , PAD , PKA , HDAC , PDE , Adenosine Receptor
Acefylline (Theophylline-7-acetic acid), a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation Etanautine to help...
TQ0067 GSK484 hydrochloride GTPL8577,AOB6992 PAD
GSK484 hydrochloride (GTPL8577) (GTPL8577) is a specifc and reversible peptidyl arginine deiminase 4 (PAD4) inhibitor. It demonstrates high-affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium.
T36107 YW3-56 YW3-56
YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4. Compared with Cl-amidine, YW3-56 shows >60-fold increase in cell growth inhibition efficacy (IC50 about 2.5 μM) but only 5-f...
T36108 YW3-56 (hydrochloride) (technical grade) YW3-56 (hydrochloride) (technical grade)
YW3-56 is an inhibitor of protein arginine deiminase 2 (PAD2) and PAD4 (IC50s = 0.5-1 and 1-5 μM, respectively).1It inhibits the growth of U2OS osteosarcoma cells (IC50= ~2.5 μM) in a p53-dependent mannerviainduction of ...
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