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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8861 | GSK199 | PAD | |
GSK199 is a selective PAD4 inhibitor(IC50 of 200 nM in the absence of calcium). | |||
T24105 | GSK121 | GSK-121,GSK 121 | PAD |
GSK121 is an inhibitor of selective PAD4. | |||
T22277 | BMS-P5 | PAD | |
BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor. | |||
T22277L | BMS-P5 free base | PAD | |
BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-... | |||
T10831L | Cl-amidine hydrochloride | Apoptosis , PAD | |
Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50: 5.9 μM for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro ca... | |||
T2205 | Acefylline | Theophylline-7-acetic acid,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid | TNF , PAD , PKA , HDAC , PDE , Adenosine Receptor |
Acefylline (Theophylline-7-acetic acid), a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation Etanautine to help... | |||
TQ0067 | GSK484 hydrochloride | GTPL8577,AOB6992 | PAD |
GSK484 hydrochloride (GTPL8577) (GTPL8577) is a specifc and reversible peptidyl arginine deiminase 4 (PAD4) inhibitor. It demonstrates high-affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. | |||
T36107 | YW3-56 | YW3-56 | |
YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4. Compared with Cl-amidine, YW3-56 shows >60-fold increase in cell growth inhibition efficacy (IC50 about 2.5 μM) but only 5-f... | |||
T36108 | YW3-56 (hydrochloride) (technical grade) | YW3-56 (hydrochloride) (technical grade) | |
YW3-56 is an inhibitor of protein arginine deiminase 2 (PAD2) and PAD4 (IC50s = 0.5-1 and 1-5 μM, respectively).1It inhibits the growth of U2OS osteosarcoma cells (IC50= ~2.5 μM) in a p53-dependent mannerviainduction of ... |